1、瓀C最(礀搀%礀礀礀讀缁缀茀螏氀頀h倀椀眀蜂錃餄餄餄猄猏猏輏伏挀琀漀瀀愀洀椀渀攀栀礀搀爀漀挀栀氀漀爀椀搀攀瀀伀挀琀漀瀀愀洀椀渀攀栀礀搀爀漀挀栀氀漀爀椀搀搀爀攀渀攀爀最椀挀刀攀挀攀瀀琀漀爀最漀渀椀猀琀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀瀀椀挀最椀昀伀挀琀漀瀀愀洀椀渀攀栀礀搀爀漀挀栀氀漀爀椀搀攀瀀伀挀琀漀瀀愀洀椀渀攀栀礀搀爀漀挀栀氀漀爀椀搀搀爀攀渀攀爀最椀挀刀攀挀攀瀀琀漀爀最漀渀椀猀琀攀搀栀瀀搀昀尀尀戀挀攀搀愀戀愀攀搀搀攀攀攀攀一椀爀搀瘀洀圀夀洀倀樀瘀洀渀氀唀砀欀瘀瘀甀琀圀瀀倀樀砀最挀堀焀琀吀唀琀攀眀伀挀琀漀瀀愀洀椀渀攀栀礀搀爀漀挀栀氀漀爀椀搀攀栀礀搀爀漀挀栀氀漀爀椀搀搀爀攀渀攀爀最椀挀刀攀挀攀瀀琀漀爀最
2、漀渀椀猀琀攀搀栀攀昀愀戀戀搀攀昀攀愀愀伀挀琀漀瀀愀洀椀渀攀栀礀搀爀漀挀栀氀漀爀椀搀攀愀琀一漀夀匀一漀蠀脀舠氀一伀舀尀摏瘯搀爀攀渀攀爀最椀挀刀攀挀攀瀀琀漀爀尀摏倀刀倀爀漀琀攀椀渀塐倀漀眀搀攀爀礀攀愀爀猀礀攀愀爀猀渀猀漀氀瘀攀渀琀洀漀渀琀栀猀洀漀渀琀栀灠湥卣鹙豛匀伀攀洀最洀洀伀攀洀最洀洀攠洀攀愀渀猀猀漀氀甀戀氀攀戀甀琀猀愀琀甀爀愀琀椀漀渀甀渀欀渀漀眀渀漀渀挀攀渀琀爀愀琀椀漀渀匀漀氀瘀攀渀琀愀猀猀洀最洀最洀最洀洀洀洀洀洀洀洀洀洀洀洀湨葎蒐伀伀吀嘀吀夀挀椯伀挀琀漀瀀愀洀椀渀攀硶蕦遑葠捶椯屓摏踯穎豽到刀一匀嬀崀刀漀攀搀攀爀吀伀挀琀漀瀀愀洀椀渀攀椀渀椀渀瘀攀爀琀攀戀爀愀琀攀猀倀爀漀最一攀甀爀漀戀椀漀氀瀀嬀
3、崀愀洀洀攀爀愀渀搀刀攀渀稀攀氀甀氀琀椀瀀氀攀猀椀琀攀猀漀昀愀猀猀漀挀椀愀琀椀瘀攀漀搀漀爀氀攀愀爀渀椀渀最愀猀爀攀瘀攀愀氀攀搀戀礀氀漀挀愀氀戀爀愀椀渀洀椀挀爀漀椀渀樀攀挀琀椀漀渀猀漀昀漀挀琀漀瀀愀洀椀渀攀椀渀栀漀渀攀礀戀攀攀猀攀愀爀渀攀洀瀀嬀崀匀挀栀甀氀稀愀渀搀刀漀戀椀渀猀漀渀伀挀琀漀瀀愀洀椀渀攀椀渀昀氀甀攀渀挀攀猀搀椀瘀椀猀椀漀渀漀昀氀愀戀漀爀椀渀栀漀渀攀礀戀攀攀挀漀氀漀渀椀攀猀漀洀瀀倀栀礀猀椀漀氀瀀挀攀倀搀昀攀椀最栀琀倀爀漀搀甀挀琀愀琀愀匀栀攀攀琀渀栀椀戀椀琀漀爀猀最漀渀椀猀琀猀匠挀爀攀攀渀椀渀最椀戀爀愀爀椀攀猀眀眀眀攀搀栀攀洀砀瀀爀攀猀猀挀渀愀甀琀椀漀渀倀爀漀搀甀挀琀栀愀猀渀漀琀戀攀攀渀昀
4、甀氀氀礀瘀愀氀椀搀愀琀攀搀昀漀爀洀攀搀椀挀愀氀愀瀀瀀氀椀挀愀琀椀漀渀猀漀爀爀攀猀攀愀爀挀栀甀猀攀漀渀氀礀吀攀氀愀砀洀愀椀氀琀攀挀栀攀搀栀攀洀砀瀀爀攀猀猀挀渀愀猀琀攀爀漀昀匀洀愀氀氀漀氀攀挀甀氀攀猀鵠蒏酶睞眀眀攀搀栀攀洀砀瀀爀攀猀猀挀渀攀搀栀攀洀砀瀀爀攀猀猀靓伀(礀搀%礀礀礀讀缁缀茀螏氀戀Octopamine-hydrochloride-()-p-Octopamine-hydrochlorid)-Adrenergic-Receptor-Agonist-MedChemExpress.pdfpic1.gifOctopaminehydrochloride(177;)pOctopaminehydroch
5、lorid)AdrenergicReceptorAgonistMedCh.pdf2019-62600bc5762-e22d-4a34-ba14-e5077ddee2ee8+NirLd+ADIvmWYHmPj6vImnlUxkvvutWp3PjxgcXBqDt/T/MUtew=Octopamine,hydrochloride,177,hydrochlorid,Adrenergic,Receptor,Agonist,MedCh664e08fa93b19bd84e26f4e38aa59947Octopamine hydrochlorideCat. No.: HY-B0528ACAS No.: 770
6、-05-8分式: CHClNO分量: 189.64作靶点: Adrenergic Receptor作通路: GPCR/G Protein储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 100 mg/mL (527.31 mM)H2O : 50 mg/mL (263.66 mM)* “ means soluble, but saturation unknown.ConcentrationSolvent Mass 1 mg 5 mg 10 mg1 mM 5.2731 mL
7、26.3657 mL 52.7315 mL5 mM 1.0546 mL 5.2731 mL 10.5463 mL制备储备液10 mM 0.5273 mL 2.6366 mL 5.2731 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液BIOLOGICAL ACTIVITY物活性 Octopamine盐酸盐是内源性的物胺，可作于肾上腺素和多巴胺系统 。REFERENCES1. Roeder, T., Octopamine in invertebrates. Prog Neurobiol, 1999. 59(5): p. 533-61.2. Hammer, M. and R. Men
8、zel, Multiple sites of associative odor learning as revealed by local brain microinjections of octopamine in honeybees. Learn Mem, 1998. 5(1-2): p. 146-56.3. Schulz, D.J. and G.E. Robinson, Octopamine influences division of labor in honey bee colonies. J Comp Physiol A, 2001. 187(1): p. 53-61.McePdf
9、HeightProduct Data Sheet InhibitorsAgonistsScreening Librarieswww.MedChemE1Caution: Product has not been fully validated for medical applications. For research use only.Tel: 400-820-3792; 021-58955995 Fax: 021-53700325 E-mail: techMedChemEMaster of Small Molecules 您边的抑制剂师www.MedChemE2MedChemExpress0
10、001500006先进医疗20190626091147058345I(鐀礀搀%礀礀鐀礀讀缁缀茀螏頀h谀椀攂蜃蜃蜃倀渀琀攀最爀椀渀渀琀愀最漀渀椀猀琀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀瀀椀挀最椀昀倀渀琀攀最爀椀渀渀琀愀最漀渀椀猀琀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀尀尀愀挀挀挀搀愀搀挀挀愀搀攀漀唀一椀欀栀氀儀瀀儀匀甀伀愀嘀樀倀洀娀戀爀唀渀栀吀礀栀刀嘀伀瀀儀倀渀琀攀最爀椀渀渀琀愀最漀渀椀猀琀攀搀栀攀洀砀瀀爀攀猀猀愀愀戀愀昀挀挀挀挀愀戀昀倀愀琀一漀夀匀一漀舀褠茀蜠丠蜀传蔀匠尀摏瘯渀琀攀最爀椀渀尀摏礀琀漀猀欀攀氀攀琀漀渀塐倀漀眀搀攀爀礀攀愀爀猀礀攀愀爀猀渀猀漀氀瘀攀渀琀洀漀渀琀栀猀洀漀渀琀栀灠湥卣鹙豛匀伀洀最洀洀一攀
11、攀搀甀氀琀爀愀猀漀渀椀挀愀渀搀眀愀爀洀椀渀最漀渀挀攀渀琀爀愀琀椀漀渀匀漀氀瘀攀渀琀愀猀猀洀最洀最洀最洀洀洀洀洀洀洀洀洀洀洀洀湨葎蒐伀伀吀嘀吀夀挀椯倀蒌椀渀琀攀最爀椀渀卓面矿靧釿瘃椀渀琀攀最爀椀渀萀渀蔀耠嬀崀刀攀攀瘀攀猀攀琀愀氀倀爀漀猀琀愀琀攀挀愀渀挀攀爀挀攀氀氀猀栀漀洀攀琀漀戀漀渀攀甀猀椀渀最愀渀漀瘀攀氀椀渀瘀椀瘀漀洀漀搀攀氀洀漀搀甀氀愀琀椀漀渀戀礀琀栀攀椀渀琀攀最爀椀渀愀渀琀愀最漀渀椀猀琀倀渀琀愀渀挀攀爀瀀爀挀攀倀搀昀攀椀最栀琀愀甀琀椀漀渀倀爀漀搀甀挀琀栀愀猀渀漀琀戀攀攀渀昀甀氀氀礀瘀愀氀椀搀愀琀攀搀昀漀爀洀攀搀椀挀愀氀愀瀀瀀氀椀挀愀琀椀漀渀猀漀爀爀攀猀攀愀爀挀栀甀猀攀漀渀氀礀吀攀氀愀砀洀愀
12、椀氀琀攀挀栀攀搀栀攀洀砀瀀爀攀猀猀挀渀愀猀琀攀爀漀昀匀洀愀氀氀漀氀攀挀甀氀攀猀鵠蒏酶睞眀眀攀搀栀攀洀砀瀀爀攀猀猀挀渀攀搀栀攀洀砀瀀爀攀猀猀靓蘁言茀渀7礀回:I叜II胔-沘輀O棙囘i缀$Glucagon-receptor-antagonists-1-Glucagon-Receptor-Antagonist-MedChemExpress.pdfpic1.gifGlucagonreceptorantagonists1GlucagonReceptorAntagonistMedChemExpress.pdf2019-6265390ce04-35a1-4794-aaab-ab8ec798309c/7zo4
13、xJGo+3OR0aM4eyiJCeA/9vHroLE+O0o7xhGpJ7Nk+z7UmE5fg=Glucagon,receptor,antagonists,Receptor,Antagonist,MedChemExpressc709d69846a27c332d46de086c8346abGlucagon receptor antagonists-1Cat. No.: HY-10036CAS No.: 503559-84-0分式: CHFNO分量: 447.58作靶点: Glucagon Receptor作通路: GPCR/G Protein储存式: Powder -20C 3 years4
14、C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 50 mg/mL (111.71 mM; Need ultrasonic)H2O : 90% corn oilSolubility: 2.75 mg/mL (6.14 mM); Clear solution1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.75 mg/mL (6.14 mM); Clear solution2. BIOLOGICAL ACTIVITY物活性 Gluca
15、gon receptor antagonists-1是活性糖素受体拮抗剂 。REFERENCES1. Ladouceur, Gaetan H. et al. Integration of optimized substituent patterns to produce highly potent 4-aryl-pyridine glucagon receptor antagonists. Bioorganic 021-58955995 Fax: 021-53700325 E-mail: techMedChemEMaster of Small Molecules 您边的抑制剂师www.MedC
16、hemE2MedChemExpress0001500006先进医疗20190626095524594349G:=炄=胔-苀輀5棙傐i缀$Trospium-chloride-mAChR-Antagonist-MedChemExpress.pdfpic1.gifTrospiumchloridemAChRAntagonistMedChemExpress.pdf2019-62668a44ce1-1c8e-4795-a715-79a3f4f18ca1UjURbmqtXy3c4ID4cegRlI74+erm8s2cJtY/roCRjEBYfG66ZYVPuQ=Trospium,chloride,mAChR
17、,Antagonist,MedChemExpressd61dc7ce69ab4ab0859b2d80bf4307d2Trospium chlorideCat. No.: HY-B0461CAS No.: 10405-02-4分式: CHClNO分量: 427.96作靶点: mAChR作通路: GPCR/G Protein; Neuronal Signaling储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 H2O : 100 mg/mL (233.67 mM)DMSO : 33.33
18、 mg/mL (77.88 mM; Need ultrasonic)* “ means soluble, but saturation unknown.ConcentrationSolvent Mass 1 mg 5 mg 10 mg1 mM 2.3367 mL 11.6833 mL 23.3667 mL5 mM 0.4673 mL 2.3367 mL 4.6733 mL制备储备液10 mM 0.2337 mL 1.1683 mL 2.3367 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液体内实验 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-
19、80 45% salineSolubility: 2.5 mg/mL (5.84 mM); Clear solution1. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (5.84 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (5.84 mM); Clear solution3. BIOLOGICAL ACTIVITY物活性 Trospium氯化物是毒蕈碱胆碱受体拮抗剂 。REFERENCESPr
20、oduct Data Sheet InhibitorsAgonistsScreening Librarieswww.MedChemE11. Staskin, D.R., Trospium chloride: Distinct among other anticholinergic agents available for the treatment of overactive bladder. Urol Clin North Am, 2006. 33(4): p. 465-73, viii.2. Doroshyenko, O., et al., Clinical pharmacokinetics of trospium chloride. Clin Pharmacokinet, 2005. 44(7): p. 701-20.McePdfHeightCaution: Product has not been fully validated for medical applications. For research use only.Tel: 400-820-3792; 021-58955995 Fax: 021-53700325
