1、脄(谀搀%谀讀缁缀氀孤節貔%頀h椀贂嬂唀倀吀开吀漀氀氀氀椀欀攀刀攀挀攀瀀琀漀爀吀刀鄀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀瀀椀挀最椀昀唀倀吀开吀漀氀氀氀椀欀攀刀攀挀攀瀀琀漀爀吀刀鄀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀尀尀挀戀昀昀戀搀戀昀搀搀愀愀搀稀嘀最挀匀昀吀吀欀儀堀欀堀稀渀倀堀椀夀挀稀匀猀焀最栀爀匀伀洀唀娀氀嘀猀漀瀀洀挀漀最唀倀吀开吀漀氀氀氀椀欀攀刀攀挀攀瀀琀漀爀吀刀鄀攀搀栀攀洀砀瀀爀攀猀猀愀戀搀昀漀琀氀椀渀攀渀栀椀戀椀琀漀爀猀最漀渀椀猀琀猀匀挀爀攀攀渀椀渀最椀戀爀愀爀椀攀猀眀眀眀攀搀栀攀洀砀瀀爀攀猀猀挀渀唀倀吀愀琀一漀夀匀一漀脀褠舀舠传蜀尀摏瘯吀漀氀氀氀椀欀攀刀攀挀攀瀀琀漀爀吀刀尀摏洀洀甀渀漀氀漀最礀渀昀氀
2、愀洀洀愀琀椀漀渀塐礀攀愀爀猀倀漀眀搀攀爀礀攀愀爀猀洀漀渀琀栀猀渀猀漀氀瘀攀渀琀洀漀渀琀栀灠湥卣鹙豛匀伀攀洀最洀洀伀最琀倀最琀最琀吀眀攀攀渀最琀最琀猀愀氀椀渀攀匀漀氀甀戀椀氀椀琀礀攀洀最洀洀氀攀愀爀猀漀氀甀琀椀漀渀鶋轏匀伀最琀最琀匀椀渀猀愀氀椀渀攀匀漀氀甀戀椀氀椀琀礀洀最洀洀匀甀猀瀀攀渀搀攀搀猀漀氀甀琀椀漀渀一攀攀搀甀氀琀爀愀猀漀渀椀挀匀蕏鹑豛愀猀琀攀爀漀昀匀洀愀氀氀漀氀攀挀甀氀攀猀鵠蒏酶睞眀眀攀搀栀攀洀砀瀀爀攀猀猀挀渀鶋轏匀伀最琀最琀挀漀爀渀漀椀氀匀漀氀甀戀椀氀椀琀礀洀最洀洀匀甀猀瀀攀渀搀攀搀猀漀氀甀琀椀漀渀一攀攀搀甀氀琀爀愀猀漀渀椀挀伀伀吀嘀吀夀挀椯唀倀吀f琀漀氀氀卓谀吀刀鄀瘀匀攀攀洀漀爀攀
3、挀甀猀琀漀洀攀爀瘀愀氀椀搀愀琀椀漀渀猀漀渀眀眀眀攀搀栀攀洀砀瀀爀攀猀猀挀渀刀刀一匀嬀崀栀攀渀最攀琀愀氀椀猀挀漀瘀攀爀礀漀昀猀洀愀氀氀洀漀氀攀挀甀氀攀椀渀栀椀戀椀琀漀爀猀漀昀琀栀攀吀刀吀刀挀漀洀瀀氀攀砀渀最攀眀栀攀洀渀琀搀渀最氀攀挀挀攀倀搀昀攀椀最栀琀愀猀琀攀爀漀昀匀洀愀氀氀漀氀攀挀甀氀攀猀鵠蒏酶睞眀眀攀搀栀攀洀砀瀀爀攀猀猀挀渀愀甀琀椀漀渀倀爀漀搀甀挀琀栀愀猀渀漀琀戀攀攀渀昀甀氀氀礀瘀愀氀椀搀愀琀攀搀昀漀爀洀攀搀椀挀愀氀愀瀀瀀氀椀挀愀琀椀漀渀猀漀爀爀攀猀攀愀爀挀栀甀猀攀漀渀氀礀吀攀氀愀砀洀愀椀氀琀攀挀栀攀搀栀攀洀砀瀀爀攀猀猀挀渀愀猀琀攀爀漀昀匀洀愀氀氀漀氀攀挀甀氀攀猀鵠蒏酶攀搀栀攀洀砀瀀爀攀猀猀
4、relatin+爀攀琀椀渀愀洀椀搀攀0ripk爀漀爀0sacubitri猀挀0shogao耀耀琀愀欀0tetracaffeoy琀最昀0trihydrat耀耀/琀甀戀攀爀挀甀氀漀猀椀猀0tyrosin甀渀戀猀0uridin+瘀愀爀搀攀渀愀昀椀氀0ve耀+瘀漀渀漀瀀爀愀稀愀渀0vp耀?眀愀爀愀渀最愀氀漀渀攀猀挀愀渀搀攀渀漀氀漀渀攀搀愀琀愀猀栀攀攀琀洀攀搀挀栀攀洀攀砀瀀爀攀猀猀瀀搀昀0wp106耀#砀攀渀0xylopentaos耀稀椀渀挀0眀zm-306416-cb-676475-datasheet-medchemexpress.pd稀猀攀琀0zylofuramin耀?耀0一朻0儀璏0刀牒0匀耀?乓
5、0匀何啓0匀呕阑0匀揯碧0匀忰0匀铰0吀0夀琄Y怡萀老舁脘搀1渀7:朼脄朼胔-摬鑻棙?i缀$Cy2 _ Dye Reagent - MedChemExpress.pdfpic1.gifCy2_DyeReagentMedChemExpress.pdf2019-1024ee1cf17d-9356-4a08-b9bd-94fd0fb4b36bTUUlSMvCruXQykCjTKFWcW6PxPiF+FFYd7UBkWlz+IPip09EH/UuNA=Cy2_DyeReagent,MedChemExpress8d104f0573a2994e40a6ef53d4e6d81eHotline: 400-82
6、0-3792Inhibitors Agonists Screening Librarieswww.MedChemECy2Cat. No.: HY-D1054分式: CHINO分量: 546.4作靶点: Others作通路: Others储存式: Please store the product under the recommended conditions in the COA.BIOLOGICAL ACTIVITY物活性 Cy2 是种花青染料，可标记多肽、蛋和寡核苷酸中的氨基，激发光和发射光波长分别为 488 nm 和 520 nm 1。REFERENCES1. Sandberg A, e
7、t al. Use of Time-Resolved Fluorescence To Improve Sensitivity and Dynamic Range of Gel-Based Proteomics. Anal Chem. 2016 Mar 15;88(6):3067-74.McePdfHeightCaution: Product has not been fully validated for medical applications. For research use only.Tel: 400-820-3792; 021-58955995 Fax: 021-53700325 E
8、-mail: techMedChemE1/1 Master of脄(搀猀讀缁缀氀孤節貔%頀h堀椀脂伂匏嬏嬏嬏茏茏茏茏茏茏茏茏茏茏茏茏茏茏茏茏茏茏蔏礀愀渀椀搀椀渀栀氀漀爀椀搀攀搀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀瀀椀挀最椀昀礀愀渀椀搀椀渀栀氀漀爀椀搀攀搀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀尀尀挀戀搀昀攀搀搀愀搀攀攀戀戀戀堀礀刀砀砀砀戀唀堀眀氀一漀匀刀氀欀砀洀匀攀欀瀀眀吀猀氀匀琀娀儀儀礀愀渀椀搀椀渀栀氀漀爀椀搀攀搀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀愀搀攀愀挀愀戀愀愀挀愀昀挀漀琀氀椀渀攀渀栀椀戀椀琀漀爀猀最漀渀椀猀琀猀匀挀爀攀攀渀椀渀最椀戀爀愀爀椀攀猀眀眀眀攀搀栀攀洀砀瀀爀攀猀
9、猀挀渀礀愀渀椀搀椀渀栀氀漀爀椀搀攀愀琀一漀夀一匀一漀匀礀渀漀渀礀洀猀搀脀蔠脀脠氀伀蘀尀摏瘯伀琀栀攀爀猀尀摏伀琀栀攀爀猀塐倀氀攀愀猀攀猀琀漀爀攀琀栀攀瀀爀漀搀甀挀琀甀渀搀攀爀琀栀攀爀攀挀漀洀洀攀渀搀攀搀挀漀渀搀椀琀椀漀渀猀椀渀琀栀攀伀伀伀吀嘀吀夀挀椯礀愀渀椀搀椀渀栀氀漀爀椀搀攀搀劂葽v驎筎矿靧豓靔屶摏礀愀渀椀搀椀渀栀氀漀爀椀搀攀搀鄀技灸潰豥一厑刀一葛桖蒏卓嬀崀匰癸礀愀渀椀搀椀渀栀氀漀爀椀搀攀搀椀渀栀椀戀椀琀猀爀攀挀攀瀀琀漀爀愀挀琀椀瘀愀琀漀爀漀昀一氀椀最愀渀搀刀一椀渀搀甀挀攀搀一愀挀琀椀瘀愀琀椀漀渀猀甀瀀瀀爀攀猀猀攀猀琀栀攀搀攀最爀愀搀愀琀椀漀渀漀昀愀渀搀愀琀琀攀渀甀愀琀攀猀琀栀攀瀀栀漀猀瀀栀漀
10、爀礀氀愀琀椀漀渀漀昀攀砀琀爀愀挀攀氀氀甀氀愀爀猀椀最渀愀氀爀攀最甀氀愀琀攀搀欀椀渀愀猀攀猀刀礀愀渀椀搀椀渀栀氀漀爀椀搀攀搀愀戀爀漀最愀琀攀猀刀一椀渀搀甀挀攀搀挀愀氀挀椀甀洀漀猀挀椀氀氀愀琀椀漀渀猀琀栀攀愀挀琀椀瘀愀琀椀漀渀漀昀渀甀挀氀攀愀爀昀愀挀琀漀爀漀昀愀挀琀椀瘀愀琀攀搀吀挀攀氀氀猀挀愀氀挀椀渀攀甀爀椀渀搀攀瀀攀渀搀攀渀琀一吀挀愀渀搀琀栀攀攀砀瀀爀攀猀猀椀漀渀漀昀挀漀猀嬀崀匀蕏癸礀愀渀椀搀椀渀栀氀漀爀椀搀攀搀瀀爀漀琀攀挀琀猀愀最愀椀渀猀琀伀嘀堀椀渀搀甀挀攀搀戀漀渀攀氀漀猀猀椀渀伀嘀堀椀渀搀甀挀攀搀漀猀琀攀漀瀀漀爀漀猀椀猀洀漀甀猀攀洀漀搀攀氀嬀崀刀刀一匀嬀崀栀攀渀最攀琀愀氀礀愀渀椀搀椀渀栀氀漀
11、爀椀搀攀椀渀栀椀戀椀琀猀漀瘀愀爀椀攀挀琀漀洀礀椀渀搀甀挀攀搀漀猀琀攀漀瀀漀爀漀猀椀猀戀礀猀甀瀀瀀爀攀猀猀椀渀最刀一洀攀搀椀愀琀攀搀漀猀琀攀漀挀氀愀猀琀漀最攀渀攀猀椀猀愀渀搀愀猀猀漀挀椀愀琀攀搀猀椀最渀愀氀椀渀最瀀愀琀栀眀愀礀猀攀氀氀倀栀礀猀椀漀氀愀爀挀攀倀搀昀攀椀最栀琀愀甀琀椀漀渀倀爀漀搀甀挀琀栀愀猀渀漀琀戀攀攀渀昀甀氀氀礀瘀愀氀椀搀愀琀攀搀昀漀爀洀攀搀椀挀愀氀愀瀀瀀氀椀挀愀琀椀漀渀猀漀爀爀攀猀攀愀爀挀栀甀猀攀漀渀氀礀吀攀氀愀砀洀愀椀氀琀攀挀栀攀搀栀攀洀砀瀀爀攀猀猀挀渀愀猀琀攀爀漀昀匀洀愀氀氀漀氀攀挀甀氀攀猀鵠蒏酶攀搀栀攀洀砀瀀爀攀猀猀攀搀挀栀攀洀攀砀瀀爀攀猀猀0medchemexpress.
12、pd耀7洀攀琀栀愀渀攀猀甀氀昀漀渀愀琀攀0唀neuropeptideyreceptorantagonis耀?耀?耀!渀渀0nn1470耀?耀?耀)渀渀0nn20耀?耀?耀#渀渀0nn3耀?耀!渀渀0nn983970耀!渀漀琀挀栀0oxyge耀瀀搀0pd耀瀀搀欀0伀prostaglandinreceptoragonis耀瀀琀0reactiveoxygenspecie耀?耀?耀%爀攀愀最攀渀琀0贀錂眂嬂輁樁鐀怀萀脁茁鸀布舜耀栀t渀7:燈釬鄀脄燈胔-摬鑻3棙?i缀$Cyclic-di-GMP-c-di-GMP-DataSheet-MedChemExpress.pdfpic1.gifCyclicdiG
13、MPcdiGMPDataSheetMedChemExpress.pdf2019-10240e20c418-0119-4422-9f43-8996180a9ddeYJX2GQRtRrs9OfndgiiOM5rcoqMX/PmOH4B7K0SIP5oC1cLsa7N51A=Cyclic,di,GMP,DataSheet,MedChemExpress12e3ed1a9b2ba58e4f02dc04ee88eecaHotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemECyclic-di-GMPCat. No.:
14、HY-107780CAS No.: 61093-23-0Synonyms: c-di-GMP; cyclic diguanylate; 5GP-5GP分式: CHNOP分量: 690.41作靶点: STING作通路: Immunology/Inflammation储存式: -20C 3 yearsPowder4C 2 years-80C 6 monthsIn solvent-20C 1 month溶解性数据体外实验 H2O : 25 mg/mL (36.21 mM)* “ means soluble, but saturation unknown.MassSolventConcentratio
15、n1 mg 5 mg 10 mg1 mM 1.4484 mL 7.2421 mL 14.4841 mL5 mM 0.2897 mL 1.4484 mL 2.8968 mL10 mM 0.1448 mL 0.7242 mL 1.4484 mL制备储备液请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Cyclic-di-GMP 是 STING 的激动剂也是个可以调节不同细菌物种的物膜形成，运动性和毒的第信使。IC50 216:149-57.2. Burdette DL, et al. STING is a dir
16、ect innate immune sensor of cyclic di-GMP. Nature. 2011 Sep 25;478(7370):515-8.McePdfHeightCaution: Product has not been fully validated for medical applications. For research use only.Tel: 400-820-3792; 021-58955995 Fax: 021-53700325 E-mail: techMedChemE2/2 Master of脄簀(搀猀怀讀缁缀氀孤節貔%勈頀h堀椀匂甄愛愛愛愛愛愛愛愛愛愛愛
17、愛愛愛愛愛愛愛挛礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀栀礀搀爀愀琀攀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀洀漀渀漀栀礀搀爀愀琀攀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀瀀椀挀最椀昀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀栀礀搀爀愀琀攀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀洀漀渀漀栀礀搀爀愀琀攀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀尀尀戀搀攀挀戀戀攀戀洀椀渀爀焀氀樀礀瀀愀攀樀儀匀圀愀戀椀刀洀瘀刀瀀搀琀欀琀戀昀嘀眀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀栀礀搀爀愀琀攀洀漀渀漀栀礀搀爀愀琀攀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀戀攀挀攀戀搀攀愀搀愀攀攀漀琀氀椀渀攀渀栀椀戀椀琀漀爀猀最漀渀椀猀琀猀匀挀爀攀攀渀椀渀最椀戀爀愀爀椀攀猀眀眀
18、眀攀搀栀攀洀砀瀀爀攀猀猀挀渀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀栀礀搀爀愀琀攀愀琀一漀夀匀一漀匀礀渀漀渀礀洀猀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀洀漀渀漀栀礀搀爀愀琀攀蜀脀蜠氀舀丠舀传茀倠尀摏瘯一氀欀礀氀愀琀漀爀爀漀猀猀氀椀渀欀攀爀尀摏攀氀氀礀挀氀攀一愀洀愀最攀塐礀攀愀爀猀倀漀眀搀攀爀礀攀愀爀猀驺摳珿罒摏灠湥卣鹙豛伀攀洀最洀洀匀伀攀洀最洀洀攠洀攀愀渀猀猀漀氀甀戀氀攀戀甀琀猀愀琀甀爀愀琀椀漀渀甀渀欀渀漀眀渀愀猀猀匀漀氀瘀攀渀琀漀渀挀攀渀琀爀愀琀椀漀渀洀最洀最洀最洀洀洀洀洀洀洀洀洀洀洀洀湨葎蒐驺摳珿罒摏伀伀吀嘀吀夀挀椯礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀栀礀搀爀愀琀攀f葢一氀欀礀氀愀琀漀爀晓箂獧矿靧酵礀挀氀漀瀀栀漀
19、猀瀀栀愀洀椀搀攀椀渀搀甀挀攀猀漀甀琀攀爀洀攀洀戀爀愀渀攀戀氀攀戀戀椀渀最氀攀愀搀猀琀漀一昀爀愀最洀攀渀琀愀琀椀漀渀愀猀爀攀瘀攀愀氀攀搀戀礀吀唀一匀癸愀猀琀攀爀漀昀匀洀愀氀氀漀氀攀挀甀氀攀猀鵠蒏酶睞眀眀攀搀栀攀洀砀瀀爀攀猀猀挀渀猀琀愀椀渀椀渀最漀昀昀爀攀攀伀一攀渀搀猀愀渀搀椀渀搀甀挀攀猀挀氀攀愀瘀愀最攀漀昀琀栀攀挀愀猀瀀愀猀攀愀渀搀挀愀猀瀀愀猀攀猀甀戀猀琀爀愀琀攀倀刀倀椀渀倀挀攀氀氀猀挀氀攀砀瀀爀攀猀猀椀漀渀昀甀氀氀礀戀氀漀挀欀猀琀栀攀愀挀琀椀瘀愀琀椀漀渀漀昀戀漀琀栀椀渀椀琀椀愀琀漀爀挀愀猀瀀愀猀攀猀愀猀眀攀氀氀愀猀琀栀攀攀昀昀攀挀琀漀爀挀愀猀瀀愀猀攀椀渀挀攀氀氀猀琀爀攀愀琀攀搀眀椀琀栀愀挀琀椀
20、瘀愀琀攀搀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀挀氀椀渀栀椀戀椀琀猀琀栀攀挀礀琀漀琀漀砀椀挀攀昀昀攀挀琀猀戀甀琀渀漀琀琀栀攀挀礀琀漀猀琀愀琀椀挀攀昀昀攀挀琀猀漀昀愀挀琀椀瘀愀琀攀搀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀嬀崀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀椀渀栀椀戀椀琀猀琀栀攀栀爀攀瘀攀爀猀椀戀氀礀眀椀琀栀愀渀漀昀嬀崀愀爀戀漀渀琀攀琀爀愀挀栀氀漀爀椀搀攀搀漀攀猀渀漀琀愀昀昀攀挀琀琀栀攀搀椀爀攀挀琀挀礀琀漀琀漀砀椀挀椀琀礀漀昀挀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀漀爀栀礀搀爀漀砀礀挀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀琀漀挀攀氀氀猀椀渀挀甀氀琀甀爀攀嬀崀匀蕏癸礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀椀渀樀攀挀琀攀搀椀瀀洀最洀漀甀猀攀椀渀
21、洀倀匀椀渀洀椀挀攀戀攀愀爀椀渀最匀圀琀甀洀漀爀猀椀渀挀爀攀愀猀攀猀琀栀攀瀀攀爀挀攀渀琀愀最攀漀昀挀攀氀氀猀琀栀愀琀猀琀愀椀渀攀搀昀漀爀漀爀椀渀戀漀琀栀猀瀀氀攀攀渀猀愀渀搀琀甀洀漀爀猀嬀崀渀椀洀愀氀漀搀攀氀匀椀砀琀漀攀椀最栀琀眀攀攀欀漀氀搀昀攀洀愀氀攀攀一洀椀挀攀戀攀愀爀椀渀最匀圀琀甀洀漀爀猀嬀崀漀猀愀最攀洀最洀漀甀猀攀搀洀椀渀椀猀琀爀愀琀椀漀渀渀樀攀挀琀攀搀椀瀀洀最洀漀甀猀攀椀渀洀倀匀漀甀爀搀愀礀猀刀攀猀甀氀琀渀挀爀攀愀猀攀搀琀栀攀瀀攀爀挀攀渀琀愀最攀漀昀挀攀氀氀猀琀栀愀琀猀琀愀椀渀攀搀昀漀爀漀爀椀渀戀漀琀栀猀瀀氀攀攀渀猀愀渀搀琀甀洀漀爀猀罢摏桓蒈漀氀攀搀攀爀氀甀渀匀攀攀洀漀爀攀挀甀猀琀漀洀攀
22、爀瘀愀氀椀搀愀琀椀漀渀猀漀渀眀眀眀攀搀栀攀洀砀瀀爀攀猀猀挀渀刀刀一匀嬀崀匀挀栀眀愀爀琀稀倀匀攀琀愀氀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀椀渀搀甀挀攀猀挀愀猀瀀愀猀攀搀攀瀀攀渀搀攀渀琀愀瀀漀瀀琀漀猀椀猀椀渀琀甀洀漀爀挀攀氀氀猀漀氀倀栀愀爀洀愀挀漀氀攀挀嬀崀愀氀愀昀愀爀椀攀琀愀氀渀栀椀戀椀琀椀漀渀漀昀栀甀洀愀渀愀挀攀琀礀氀挀栀漀氀椀渀攀猀琀攀爀愀猀攀戀礀挀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀吀漀砀椀挀漀氀漀最礀愀渀嬀崀愀爀爀椀猀刀一攀琀愀氀愀爀戀漀渀琀攀琀爀愀挀栀氀漀爀椀搀攀椀渀搀甀挀攀搀椀渀挀爀攀愀猀攀椀渀琀栀攀愀渀琀椀琀甀洀漀爀愀挀琀椀瘀椀琀礀漀昀挀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀椀渀洀椀挀攀愀瀀栀愀爀洀愀
23、挀漀欀椀渀攀琀椀挀猀琀甀搀礀愀渀挀攀爀栀攀洀漀琀栀攀爀倀栀愀爀洀愀挀漀氀嬀崀椀甀倀攀琀愀氀搀洀椀渀椀猀琀爀愀琀椀漀渀漀昀挀礀挀氀漀瀀栀漀猀瀀栀愀洀椀搀攀挀栀愀渀最攀猀琀栀攀椀洀洀甀渀攀瀀爀漀昀椀氀攀漀昀琀甀洀漀爀戀攀愀爀椀渀最洀椀挀攀洀洀甀渀漀琀栀攀爀愀渀挀攀倀搀昀攀椀最栀琀愀甀琀椀漀渀倀爀漀搀甀挀琀栀愀猀渀漀琀戀攀攀渀昀甀氀氀礀瘀愀氀椀搀愀琀攀搀昀漀爀洀攀搀椀挀愀氀愀瀀瀀氀椀挀愀琀椀漀渀猀漀爀爀攀猀攀愀爀挀栀甀猀攀漀渀氀礀吀攀氀愀砀洀愀椀氀琀攀挀栀攀搀栀攀洀砀瀀爀攀猀猀挀渀愀猀琀攀爀漀昀匀洀愀氀氀漀氀攀挀甀氀攀猀鵠蒏酶攀搀栀攀洀砀瀀爀攀猀猀稀洀0zse耀?耀+稀甀爀愀渀漀氀漀渀攀0zylof
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