1、MilrinoneCat. No.: HY-14252CAS No.: 78415-72-2Molecular Formula: CHNOMolecular Weight: 211.22Target: Phosphodiesterase (PDE)Pathway: Metabolic Enzyme/ProteaseStorage: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 monthSolvent initial bolus of 1.6 mL/kg, followed by 10 L/kg/h) are admin
2、istered by an infusion pump for 10 min.MCE has not independently confirmed the accuracy of these methods. They are for reference only.REFERENCES1. Santhosh KT, et al. Milrinone attenuates thromboxane receptor-mediated hyperresponsiveness in hypoxic pulmonary arterial myocytes. Br J Pharmacol. 2011 J
3、ul;163(6):1223-36.2. Hentschel T, et al. Inhalation of the phosphodiesterase-3 inhibitor milrinone attenuates pulmonary hypertension in a rat model of congestive heart failure. Anesthesiology. 2007 Jan;106(1):124-31.3. Kishi T, et al. Effects of milrinone on left ventricular end-systolic pressure-vo
4、lume relationship of rat hearts in situ. Clin Exp Pharmacol Physiol. 2001 Sep;28(9):737-42.4. Taylor MS, et al. Effect of milrinone on small mesenteric artery vasoconstriction: role of K(+) channels. Am J Physiol. 1999 Jul;277(1 Pt 1):G69-78.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAwww.MedChemE2
