1、MSX-122Cat. No.: HY-13696CAS No.: 897657-95-3Molecular Formula: CHNMolecular Weight: 292.34Target: CXCRPathway: GPCR/G Protein; Immunology/InflammationStorage: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 monthSolvent (ii) ease of production on a large scale; (iii) effectiveness as an
2、 anti-inflammatory and anti-metastatic agent in vivo; and (iv) unique property of blocking homing and recruitment without mobilizing stem cells. MSX-122 blocks invasion and angiogenesis in vitro.in vivo: MSX-122 attenuates colonic damage in mice with experimental colitis.MSX-122 blocks metastasis in
3、 an experimental animal model of breast cancer metastasis. MSX-122 blocks metastasis in two more animal models for metastasis.REFERENCES1. Liang Z, et al. Development of a unique small molecule modulator of CXCR4. PLoS One. 2012;7(4):e34038.Product Data Sheet InhibitorsAgonistsScreening Librarieswww.MedChemE1Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAwww.MedChemE2
