1、Toltrazuril sulfoneCat. No.: HY-17008CAS No.: 69004-04-2Molecular Formula: CHFNOSMolecular Weight: 457.38Target: ParasitePathway: Anti-infectionStorage: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 monthSolvent Ryman, Josiah T.; Boileau, Melanie J.; Martin-Jimenez, Tomas; Meibohm, Ber
2、nd From American Journal of Veterinary Research (2011), 72(10), 1386-1389Product Data Sheet InhibitorsAgonistsScreening Librarieswww.MedChemE12. Dirikolu L, Karpiesiuk W, Lehner AF, Tobin T. Toltrazuril sulfone sodium salt: synthesis, analytical detection, and pharmacokinetics in the horse. J Vet Ph
3、armacol Ther. 2012 Jun;35(3):265-74. doi: 10.1111/j.1365-2885.2011.01315.x.3. Lim JH, Kim MS, Hwang YH, Song IB, Park BK, Yun HI. Pharmacokinetics of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, after a single oral administration to pigs. J Vet Med Sci. 2010 Aug;72
4、(8):1085-7.4. Dirikolu L, Yohn R, Garrett EF, Chakkath T, Ferguson DC. Detection, quantifications and pharmacokinetics of toltrazuril sulfone (Ponazuril) in cattle. J Vet Pharmacol Ther. 2009 Jun;32(3):280-8.5. Dirikolu L, Karpiesiuk W, Lehner AF, Hughes C, Granstrom DE, Tobin T. Synthesis and detec
5、tion of toltrazuril sulfone and its pharmacokinetics in horses following administration in dimethylsulfoxide. J Vet Pharmacol Ther. 2009 Aug;32(4):368-78.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAwww.MedChemE2