1、鼼3鼀(开搀怀开开开讀缁缀謚漁螏頀h堀椀錂脃鼃鼑鼑丒堀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀瀀椀挀最椀昀一堀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀尀尀愀攀愀挀挀昀昀愀愀戀攀戀攀搀愀夀刀攀焀渀稀洀一焀一倀唀礀砀最伀瘀爀砀搀嘀唀焀猀刀焀眀一堀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀搀挀攀搀挀戀挀昀戀一堀愀琀一漀夀匀一漀漀氀攀挀甀氀愀爀漀爀洀甀氀愀舀茠茀茠丠茀传蠀漀氀攀挀甀氀愀爀圀攀椀最栀琀吀愀爀最攀琀渀最椀漀琀攀渀猀椀渀挀漀渀瘀攀爀琀椀渀最渀稀礀洀攀倀愀琀栀眀愀礀攀琀愀戀漀氀椀挀渀稀礀洀攀倀爀漀琀攀愀猀攀匀琀漀爀愀最攀倀氀攀愀猀攀猀琀漀爀攀琀栀攀瀀爀漀搀甀挀琀甀渀搀攀爀琀栀攀爀攀挀漀洀洀
2、攀渀搀攀搀挀漀渀搀椀琀椀漀渀猀椀渀琀栀攀伀匀漀氀瘀攀渀琀洀最欀最愀爀攀椀渀樀攀挀琀攀搀搀甀爀椀渀最椀渀昀甀猀椀漀渀漀昀攀渀愀氀愀瀀爀椀氀一堀漀爀猀愀氀椀渀攀椀渀昀甀猀椀漀渀吀栀攀氀一椀猀椀渀昀甀猀攀搀愀琀愀爀愀琀攀漀昀洀洀椀渀漀瘀攀爀洀椀渀昀漀爀攀愀挀栀搀漀猀攀琀琀栀攀攀渀搀漀昀攀愀挀栀椀渀昀甀猀椀漀渀琀栀攀爀攀猀甀氀琀椀渀最栀愀攀洀漀搀礀渀愀洀椀挀挀栀愀渀最攀猀愀爀攀爀攀挀漀爀搀攀搀吀栀攀琀漀琀愀氀搀漀猀攀愀搀洀椀渀椀猀琀攀爀攀搀漀昀渀椀洀愀氀搀洀椀渀椀猀琀爀愀琀椀漀渀嬀崀倀爀漀搀甀挀琀愀琀愀匀栀攀攀琀渀栀椀戀椀琀漀爀猀最漀渀椀猀琀猀匠挀爀攀攀渀椀渀最椀戀爀愀爀椀攀猀眀眀眀攀搀栀攀洀砀瀀爀攀
3、猀猀挀漀洀一堀愀渀搀攀渀愀氀愀瀀爀椀氀琀栀爀漀甀最栀漀甀琀琀栀攀瀀爀漀琀漀挀漀氀猀椀猀愀渀搀洀漀氀欀最爀攀猀瀀攀挀琀椀瘀攀氀礀吀栀攀栀愀攀洀漀搀礀渀愀洀椀挀瘀愀爀椀愀戀氀攀猀愀爀攀洀攀愀猀甀爀攀搀戀攀昀漀爀攀愀渀搀愀昀琀攀爀攀愀挀栀氀一搀漀猀攀椀渀愀氀氀最爀漀甀瀀猀吀栀攀倀愀渀搀刀愀爀攀搀椀猀瀀氀愀礀攀搀挀漀渀琀椀渀甀漀甀猀氀礀漀渀愀挀漀洀瀀甀琀攀爀洀漀渀椀琀漀爀愀渀搀愀爀攀爀攀挀漀爀搀攀搀漀渀愀瀀爀椀渀琀攀爀挀漀甀瀀氀攀搀琀漀琀栀椀猀猀礀猀琀攀洀攀愀猀甀爀攀洀攀渀琀猀漀昀琀栀攀栀愀攀洀漀搀礀渀愀洀椀挀攀瘀攀渀琀猀愀爀攀瀀攀爀昀漀爀洀攀搀椀渀琀爀椀瀀氀椀挀愀琀攀昀漀爀攀愀挀栀琀椀洀攀瀀攀爀椀漀
4、搀栀愀猀渀漀琀椀渀搀攀瀀攀渀搀攀渀琀氀礀挀漀渀昀椀爀洀攀搀琀栀攀愀挀挀甀爀愀挀礀漀昀琀栀攀猀攀洀攀琀栀漀搀猀吀栀攀礀愀爀攀昀漀爀爀攀昀攀爀攀渀挀攀漀渀氀礀刀刀一匀嬀崀眀愀渀愀最愀夀攀琀愀氀渀椀琀爀椀挀漀砀椀搀攀爀攀氀攀愀猀椀渀最搀攀爀椀瘀愀琀椀瘀攀漀昀攀渀愀氀愀瀀爀椀氀一堀瀀爀攀瘀攀渀琀猀瀀爀漀最爀攀猀猀椀瘀攀挀愀爀搀椀愀挀搀礀猀昀甀渀挀琀椀漀渀愀渀搀爀攀洀漀搀攀氀椀渀最椀渀栀愀洀猀琀攀爀猀眀椀琀栀栀攀愀爀琀昀愀椀氀甀爀攀匀愀爀瀀甀戀愀渀嬀崀伀欀甀礀愀洀愀攀琀愀氀倀栀愀爀洀愀挀漀欀椀渀攀琀椀挀猀愀渀搀瀀栀愀爀洀愀挀漀搀礀渀愀洀椀挀猀漀昀愀渀椀琀爀椀挀漀砀椀搀攀爀攀氀攀愀猀椀渀最搀攀爀椀瘀愀琀椀
5、瘀攀漀昀攀渀愀氀愀瀀爀椀氀椀渀洀愀氀攀戀攀愀最氀攀猀氀椀渀砀瀀倀栀愀爀洀愀挀漀氀倀栀礀猀椀漀氀瀀爀愀甀琀椀漀渀倀爀漀搀甀挀琀栀愀猀渀漀琀戀攀攀渀昀甀氀氀礀瘀愀氀椀搀愀琀攀搀昀漀爀洀攀搀椀挀愀氀愀瀀瀀氀椀挀愀琀椀漀渀猀漀爀爀攀猀攀愀爀挀栀甀猀攀漀渀氀礀吀攀氀愀砀洀愀椀氀琀攀挀栀攀搀栀攀洀砀瀀爀攀猀猀挀漀洀搀搀爀攀猀猀攀攀爀倀愀爀欀爀匀甀椀琀攀儀漀渀洀漀甀琀栀甀渀挀琀椀漀渀一唀匀眀眀眀攀搀栀攀洀砀瀀爀攀猀猀挀漀洀攀搀栀攀洀砀瀀爀攀猀猀靓一言茀渀7开帝:鄬3D鼼3鄬3胔-輀$棙i缀$NEO-376-DataSheet-MedChemExpress.pdfpic1.gifNEO376DataSheet
6、MedChemExpress.pdf2019-5317582ad95-fb28-49ec-b654-cfc3df8234dejEEuVttan/rOViIHu1tCrLUSRAUJ8jK1E+V/atkhU5WHMLfQDwDhmw=NEO,376,DataSheet,MedChemExpress89cc3041e4d4c9e3943c8d71874c08c8NEO 376Cat. No.: HY-101583CAS No.: 496921-73-4Molecular Formula: CHClNOMolecular Weight: 357.88Target: 5-HT Receptor; G
7、ABA Receptor; Dopamine ReceptorPathway: GPCR/G Protein; Neuronal Signaling; Membrane Transporter/Ion ChannelStorage: Please store the product under the recommended conditions in the COA.Solvent & SolubilityIn Vitro 10 mM in DMSOConcentrationSolvent Mass 1 mg 5 mg 10 mg1 mM 2.7942 mL 13.9712 mL 27.94
8、23 mL5 mM 0.5588 mL 2.7942 mL 5.5885 mLPreparing Stock Solutions10 mM 0.2794 mL 1.3971 mL 2.7942 mLPlease refer to the solubility information to select the appropriate solvent.BIOLOGICAL ACTIVITYDescription NEO 376 is a selective modulator of 5-HT1 receptor, GABA receptor and dopamine receptor, with
9、 anti-psychotic actively.REFERENCES1. David B. Fick, et al. Tetrahydroindolone and purine derivatives linked to arylpiperazines. US 6770638 B2Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAProduct Data Sheet InhibitorsAgonistsScreening Librarieswww.MedChemE1MedChemExpress0001500006先进医疗20190531141331391896N
