1、AF-353Cat. No.: HY-14483CAS No.: 865305-30-2Molecular Formula: CHINOMolecular Weight: 400.21Target: P2X ReceptorPathway: Membrane Transporter/Ion ChannelStorage: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 monthSolvent however, the frequency of NVC in SCI rats was significantly reduc
2、ed.2REFERENCES1. Gever JR, et al. AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist. Br J Pharmacol. 2010 Jul;160(6):1387-1398.Product Data Sheet InhibitorsAgonistsScreening Librarieswww.MedChemE12. Munoz A, et al. Modulation of bladder afferent signals in normal and sp
3、inal cord-injured rats by purinergic P2X3 and P2X2/3receptors. BJU Int. 2012 Oct;110(8 Pt B):E409-414.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAwww.MedChemE2
