1、BAY-8002Cat. No.: HY-122312CAS No.: 724440-27-1Molecular Formula: CHClNOSMolecular Weight: 415.85Target: Monocarboxylate TransporterPathway: Membrane Transporter/Ion ChannelStorage: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 monthSolvent Need ultrasonic)H2O : 90% corn oilSolubility:
2、 2.08 mg/mL (5.00 mM); Clear solution1. Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (5.00 mM); Clear solution2. Add each solvent one by one: 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (5.00 mM); Suspended solution; Need ultrasonic3. BI
3、OLOGICAL ACTIVITYDescription BAY-8002 is a potent, selective, orally active inhibitor of monocarboxylate transporter 1 (MCT1), with an IC50 of 85 nM in the MCT1-expressing DLD-1 cells, displays excellent selectivity against MCT4. Anti-tumor activity1.IC 17(11):2285-2296.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAwww.MedChemE2
