1、BSc5371Cat. No.: HY-111545CAS No.: 2286419-03-0Molecular Formula: CHNOSMolecular Weight: 485.6Target: FLT3Pathway: Protein Tyrosine Kinase/RTKStorage: Please store the product under the recommended conditions in the COA.BIOLOGICAL ACTIVITYDescription BSc5371 is a potent and irreversible FLT3 inhibit
2、or, with Kds of 1.3, 0.83, 1.5, 5.8 and 2.3 nM for mutant FLT3(D835H), FLT3(ITD, D835V), FLT3(ITD, F691L), FLT3-ITD and wild type FLT3wt, respectively. BSc5371 is cytotoxic to FLT3-dependent cell lines1.IC 62(5):2428-2446.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAProduct Data Sheet InhibitorsAgonistsScreening Librarieswww.MedChemE1
