1、CA-5fCat. No.: HY-112698CAS No.: 1370032-19-1Molecular Formula: CHNOMolecular Weight: 388.46Target: AutophagyPathway: AutophagyStorage: Please store the product under the recommended conditions in the COA.Solvent Need ultrasonic)H2O : 90% corn oilSolubility: 2.08 mg/mL (5.35 mM); Clear solution1. Ad
2、d each solvent one by one: 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (5.35 mM); Suspended solution; Need ultrasonic2. Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (5.35 mM); Clear solution3. BIOLOGICAL ACTIVITYDescription CA-5f is a po
3、tent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. CA-5f increases LC3B-II (a marker to monitor autophagy) and SQSTM1 protein both in A549 cells and HUVECs. Anti-tumor activity1.IC 15(3):391-406.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAwww.MedChemE2
