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因素监测与干预工作方案 .pdf

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1、emistry and biology. It is not surprising that most of the licensed antiviral drugs (e.g. Zovirax and AZT) and many anticancer drugs are nucleoside analogues which are able to interfere with nucleic acid biosynthesis in a selective manner. Additionally, much of the recent information on the structur

2、e/function relationship of nucleic acids has come from using DNA/RNA probes that contain a subtle chemical modification. Present work within the group is concerned with studies on the synthesis of novel nucleic acids analogues as both potential therapeutic agents and as probes for understanding the

3、precise mechanism by which nucleic acids fulfill their biological functions。 (相关链接:https:/www.liverpool.ac.uk/chemistry/staff/richard- cosstick/research/) 5. Shchukin 教授新材料,新能源(Prof. Dmitry Shchukin, works on controlled delivery of active agents and energy (electric, bio, thermal) by Layer-by-Layer

4、planar and encapsulation approaches (250 publications, H-factor 60, 10000 citations). He has been awarded by ERC Consolidator grant (2015), ERC Proof-of-concept grant (2017), and RSC Brian Mercer (UK) awards, Nanofutur and ForMat (Germany) prizes. Research activities include the study of the non-equ

5、ilibrated interfaces, development of composite hollow nanocontainers with controlled shell permeability for encapsulation of the energy-enriched materials, phase change materials, drugs, corrosion inhibitors; development of nanocontainer-based feedback active surfaces for further application in acti

6、ve self-healing materials, catalysis, biochemistry and medicine; synthesis of nanomaterials with new properties in the ultrasonic cavitation zone, synthesis of amorphous nanocomposites with enhanced catalytic performance in non-equilibrated conditions at the cavitation interface; ultrasonic surface

7、modification of metals for catalytic and biomedical (implants) applications. Applications from students with the background in materials chemistry, polymer chemistry, ultrasound, physical chemistry, self-healing materials, energy harvesting, storage and controlled delivery and other related fields.

8、Potential research topics are: 1) new nanomaterials for energy applications;2)- self-healing materials (also including materials for wood and historical heritage preservation); 3) antifouling coatings; 4) application of ultrasound in photocatalysis and photovoltaics) 相关链接:https:/www.liverpool.ac.uk/

9、chemistry/staff/dmitry-shchukin/, 6. Aissa 副教授有机合成化学,精准催化合成 (Christophe Assa obtained his PhD under the supervision of Professor Malacria (University Paris 6, France) in 2001, focussing on the study of the factors influencing the outcome of transannular radical cyclisations cascades directed toward

10、the synthesis of natural sesquiterpenes. He then joined Professor Frstner group (MPI for coal research, Mlheim/Ruhr, Germany) as postdoctoral research assistant, working on the total synthesis of biologically active marine secondary metabolites. In 2003, he was appointed senior scientist within the

11、same group, working further on total syntheses, but also on transition-metal catalysed reactions. In July 2007, he was appointed Lecturer at The University of Liverpool with a RCUK fellowship 。 His group works on organic synthesis through transition-metal-catalysed activation of otherwise inert bond

12、s, in particular CH and CC bonds, with the long-term aim to develop sustainable synthetic chemistry. Here is a selection of papers that illustrate their work : Barday, M.; Janot, C.; Halcovitch, N. R.; Muir, J.; Assa, C. Cross- Coupling of -Carbonyl Sulfoxonium Ylides with CH Bonds. Angew. Chem. Int

13、. Ed. 2017, 56, 13117 13121.2)Yip, S. Y. Y.; Assa, C. Isomerization of Olefins Triggered by Rhodium-Catalyzed CH Bond Activation: Control of Endocyclic -Hydrogen Elimination. Angew. Chem. Int. Ed. 2015, 54, 68706873. 3)Assa, C.; Ho, K. Y. T.; Tetlow, D. J.; Pin-No, M. Diastereoselective Carbocycliza

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