1、647g11149g11161g8614g4658(genus Morbillivirus)g452g4439g7171g980g12193g7389g2265g14192g11352g2345g19154RNAg11161g8614g712g6980g2325g5192g7481g3324g1852g10711g14551g3272g1881g3355g1457g6357g1038g2345g980g6251g2419g3423g452g3534g3252g13464g13546g11733g2265g6336g15892g1969g13044g15519g11345(haemaggluti
2、nin protein, H) g2656g15713g2524g15519g11345(fusion protein, 1 Brenzel L et al. Disease control priorities in developing countries. In: Cairns KL et al, eds. Vaccine-preventable diseases. Washington, DC, The International Bank for Reconstruction and Development/The World Bank, 2006:389411. (Also ava
3、ilable from http:/files.dcp2.org/pdf/expressbooks/vaccine.pdf). 2 g16277No. 49, 2008, pp. 441448. 2 F)g3324g1881g113528g12193g15519g11345g17148g452g5751g13785g3324g5875g7591g21647g11149g11161g8614g2530g2499g14731g5483g13468g10995g1825g11135g2159g712g17837g5483g11422g1122g7438g1319g1147g10995g11352g6
4、251Hg15519g11345g1025g2656g6251g1319g4523g4557g21647g11149g11161g8614g3534g3252g13464g11352g8991g5219g17816g1182g5062g2469g10628g111423g12193g993g2528g11352g3534g3252g3423g712g2499g11004g1122g17873g17406g21647g11149g11352g1268g6785g4524 g3324g9520g1251g7411g7423g7411g712g5751g13785g1998g10628g20652g
5、9921g451g2695g3025g451g21775g9826g2656g13479g14192g9826g12573g2081g20549g11163g10378g45234g3837g2530g5751g13785g2499g1998g10628g1868g3423g11352g7013g1004g11149g712g5132g1288g7389g20652g178103940 Cg11352g2469g9921g452g3324g1998g11149g7114g2499g1122g2487g20062g12908g14192g990g1147g10995g21647g11149g10
6、317g7389g11352g5114g8985g15025g14406g11352g11345g7013g708Koplikg7013g709g452g1998g11149g2530g125443g3837g5751g13785g11161g5785g17902g5132g2499g3921g17728g712g5194g1122g17227g11161g2530710g3837g4448g1852g5259g3809g452 g21647g11149g11352g1017g18337g12255g5242g5058g5334g5468g3835g712g2474g1927g1122g449
7、9g1039g2656g10627g3671g12573g16780g3822g3252g13044g452g1017g18337g11352g6122g14280g8527g5627g21647g11149g11352g20652g2373g3252g13044g2265g6336g726g5192g21848g33245g4693g1209g991g727g10995g8975g3324g17819g5242g6329g6392g11352g10627g3671g1025g727g14841g1871g993g14403g708g17902g5132g7171g13512g10995g13
8、044Ag13582g1059g709g727g1825g11135g13007g13491g11154g11161g712g3926HIVg5875g7591g7214g7411g452g3324g2469g4649g1025g3281g4490g712g21647g11149g3324g5200g1811g1025g11352g11161g8527g10587g2499g17810 5%10%g4525g3324g5049g1006g2282g3281g4490g712g21647g11149g14280g8527g13609g16277g712g993g17819g712g3324g70
9、94g5460g1593g5259g11352g1166g2604g1025g2469g10995g18337g3423g21647g11149g1047g14279g8527g1141g11352g11161g1375g1075g1610g7389g6265g2590g452g21647g11149g17751g5132g16277g11352g5194g2469g11163g2265g6336g1025g13831g9826g451g2909g8680g12661g6915g8680g12661g9826g2656g13966g9826g452g3324g1811g12473g11161g
10、1375g1025g712g1025g13831g9826g11352g2469g10995g10587g10385%15%g712g13966g9826g10385%10%g452g3324g2469g4649g1025g3281g4490g712g5751g13785g708g4600g1866g7171g4168g5200g1811g709g2499g2469g10995g6357g13505g14157g8911g1288g15519g11345g17148g1014g3845g5627g13940g11161g452g3324g21647g11149g11161g1375g1025g
11、712g5625g5627g21647g11149g2530g14053g9826g11352g2469g10995g10587g13434g10381/1000g712g1134g5625g5627g11840g2282g5627g1852g14053g9826g708g980g12193g17839g4649g13543g5942g11352g1025g7542g12082g13475g13007g13491g5875g7591g709g11352g2469g10995g10587g13434g1038g2325g987g2010g1055g980g14279g987g2010g1055g
12、980g4526 麻疹和维生素A g13512g10995g13044 A g13582g1059g2499g4560g14280g5259g3809g13543g5942g1209g2462g21647g11149g5194g2469g11163g2469g10995g10587g2331g20652g452g8504g3818g712g21647g11149g5875g7591g1075g2499g2164g2107g13512g10995g13044 A g13582g1059g2656g13479g14192g5190g10169g11163g452g3252g8504g712g738
13、9g11468g5415g3835g980g18108g2010g2499g20056g19462g11352g1811g12473g11462g7171g11013g21647g11149g6164g14280g708g4600g1866g7171g3324g19762g8966g709g452 g3324g21647g11149g8847g11115g7411g19400g712g13485g1116 2 g1022g2070g8437g11352g13512g10995g13044 A g2499g1147g10995g14403g3921g6940g7536g712g17837g980
14、g9869g5062g15999g1817g2010g16789g4466g4527WHOg5415g2081g11352g7053g190368g7171g1525g4560g4557g6164g7389g5625g5627g21647g11149g11161g1375g13485g11162g1022g2070g8437g11352g13512g10995g13044Ag452g2499g3324g1328g1998g16798g7041g2530g2375g2063g13485g1116g3835g2070g18339g13512g10995g13044Ag712g5194g1122g8
15、437g7097g13485g1116g125442g1022g2070g8437g452WHOg6524g14628g11352g5192g21848g2047g8611g7097g2070g18339g3926g991g7266g7388g21848g1209g991g4168g1811g71250 000 IUg727611g7388g21848g712100 000 IUg727g30512g7388g21848g712200 000 IUg452g3926g7536g1811g12473g7389g13512g10995g13044Ag13582g1059g11352g1032g52
16、14g11163g10378g708g3926Bilotg7013g709g712g2499g332446g2620g2530g13485g1116g125443g1022g2070g8437g452g2375g1427g7171g3324g21647g11149g11163g10378g17902g5132g5194g993g1017g18337g11352g3281g4490g712g4557g1122g6164g7389g1017g18337g21647g11149g11161g1375g1075g5224g13485g1116g13512g10995g13044Ag452 暴露于麻疹后
17、的保护性免疫力9 g15441g9994g5502g10627g13007g13491g1025g11352g6251 H g6251g2419g1025g2656g6251g1319g11352g4396g3324g17287g1209g20056g19462g21647g11149g11161g8614g5875g7591g712g1306g7171g980g70983 de Swart RL, Yuksel S, Osterhaus AD. Relative contributions of measles virus hemagglutinin- and fusion protein-
18、specific serum antibodies to virus neutralization. Journal of Virology, 2005, 79:11547115451. 4 Rota PA, Featherstone DA, Bellini WJ. Molecular epidemiology of measles virus. Current Topics in Microbiology and Immunology, 2009, 330:129150. 5 Wolfson LJ et al. Estimates of measles case fatality ratios: a comprehensive review of community-based studies. International Journal of Epidemiology, 2009, 38:192205. 6
